Hexametaphosphate‐Capped Silica Mesoporous Nanoparticles Containing CuII Complexes for the Selective and Sensitive Optical Detection of Hydrogen Sulfide in Water

Cu^II‐macrocycle functionalized hexametaphosphate‐capped silica mesoporous nanoparticles have been prepared and used for the selective and sensitive detection of hydrogen sulfide in aqueous environments. The possibility of using different metal complexes combined with different capping anions and choice of different dyes or other sensing molecules as indicators makes this new protocol highly appealing for the preparation of new sensing systems for sulfide detection in different environments.     

De-noising of wayside acoustic signal from train bearings based on variable digital filtering

In the wayside Acoustic Defective Bearing Detector (ADBD) system, the recorded signal usually includes both the sound from train bearings and the other disturbance sources. The fact of heavy noise corruption and the Doppler Effect of multi-source acoustic signals would badly reduce the effectiveness of online defect detection of the ADBD system. In order to extract useful information from the multi-source signal with Doppler Effect, this paper proposes an effective de-noising method based on the variable digital filter (VDF) for the ADBD system. Specifically, the ridge extraction based on Short-Time Fourier Transform (STFT) is applied to estimate the instantaneous frequencies (IFs), with which the fitting IF curves based on the Morse theory of theoretical acoustics could be achieved by using the nonlinear curve-fitting so that the parameters of the initial position of the acoustic sources could be calculated. By the aid of these parameters, the IFs according to the target train bearing could be then extracted. After that, the FIR variable digital filters could be designed with all the IFs which match the Morse theory with Doppler Shift so that the noise from the other parts could be effectively restrained after filtering the original signal. The effectiveness of this method is verified by means of a simulation with multi-frequency signals and applications to diagnosis of train roller bearing defects. Results indicate that the proposed method is effective.     

New relationship of displacement signal at quadrant photodiode: Control signal analysis and simulation of a laser tracker

New relationship of displacement signal using opposite sectors on a quadrant photodiode is derived. Standard and new displacement signals are analyzed in details. Through MATLAB^® laser tracking simulation models, based on common and suggested approaches, detailed analysis is performed, and it is shown that better results for the new relationship signal processing are obtained. Within new relationship of displacement signal, the sensitivity of the system to the displacement of the spot increases and, hence, provides better accuracy in positioning up to 30%.     

Nmr and Mass Spectroscopic Studies of the Competitive-Angiotensin II Antagonist “Sarmesin”

Fast atom bombardment mass spectrometry (FAB-MS) and high resolution (400 Mz) proton nuclear magnetic resonance (NMR spectroscopy) on the competitive angiotensin II antagonist, |Sar¹, Tyr(Me)⁴ (ANGII (Sarmesin) and its he-ptapeptide homolog, [Tyr(Me)³ |ANGIII, yield spectra which provide confirmation of structure and molecular weight. The characteristics of the spectra are discussed and compared with the spectra of natural ANG II, ANG III and |Sar¹|ANG II. The NMR data are suggestive of interactions in angiotensin between: 1) the phenolic hydroxyl group and the imidazole ring, and 2) the N-terminal amino group and the Tyrring. These interactions may be important for the formation of the proposed charge transfer system in angiotensin II involving the phenoxyl and α-carboxylate groups.     

Selectivity of seismic electric signal (SES) of the 2000 Izu earthquake swarm: a 3D FEM numerical simulation model

Although seismic electric signal (SES) has been used for short-term prediction of earthquakes, selectivity of SES still remains as one of the mysterious features. As a case study, we made a numerical simulation based on a 3D finite element method (FEM) on the selectivity of SES observed in the case of the 2000 Izu earthquake swarm. Our numerical results indicated that the existence of conductive channel under Niijima island could explain the reported SES selectivity.     

Fiber optical parametric amplifiers in optical communication systems

The prospects for using fiber optical parametric amplifiers (OPAs) in optical communication systems are reviewed. Phase‐insensitive amplifiers (PIAs) and phase‐sensitive amplifiers (PSAs) are considered. Low‐penalty amplification at/or near 1 Tb/s has been achieved, for both wavelength‐ and time‐division multiplexed formats. High‐quality mid‐span spectral inversion has been demonstrated at 0.64 Tb/s, avoiding electronic dispersion compensation. All‐optical amplitude regeneration of amplitude‐modulated signals has been performed, while PSAs have been used to demonstrate phase regeneration of phase‐modulated signals. A PSA with 1.1‐dB noise figure has been demonstrated, and preliminary wavelength‐division multiplexing experiments have been performed with PSAs. 512 Gb/s have been transmitted over 6,000 km by periodic phase conjugation. Simulations indicate that PIAs could reach data rate x reach products in excess of 14,000 Tb/s × km in realistic wavelength‐division multiplexed long‐haul networks. Technical challenges remaining to be addressed in order for fiber OPAs to become useful for long‐haul communication networks are discussed.

     

A novel signal-on fluorescent aptasensor for ochratoxin A detection based on RecJf exonuclease-induced signal amplification

This article describes a simple and homogeneous fluorescent aptasensor for the detection of ochratoxin A (OTA). With its high specificity and simplicity; RecJ_f exonuclease is used to cleave DNA strand of the FAM-aptamer/OTA complex and realize target recycling signal amplification. In order to avoid the loss of reaction system, magnetic beads (MBs) are added only once at the last experimental step. This proposed fluorescent aptasensor showed the higher sensitivity in the range of 0.1–100 ng/mL with LOD of 0.056 ng/mL, and the good selectivity against other interfering toxins. The feasibility of the prepared aptasensor was studied by detecting OTA in spiked liquor and cereal samples. The obtained average recoveries ranged from 92% to 115%. This study provides a promising application with convenience and rapidness in the aptasensor fabrication for food safety analysis.     

飞行时间质谱仪四极杆射频信号放大器的研制

根据自制质谱仪需求研制了一种射频放大装置,由放大电路模块和耦合线圈构成,将其与射频信号发生装置结合用以驱动射频四极杆.该射频放大器可将射频信号放大30倍,为自制射频四极杆提供共振频率1.4 MHz,射频电压峰峰值电压Vp-p可调范围0～600 V的射频信号.自制四极杆用于传输大气压下离子源产生的离子从离子源至工作在高真...     

Long‐Wavelength Fluorescent Reporters for Monitoring Protein Kinase Activity

In vivo optical imaging must contend with the limitations imposed by the optical window of tissue (600–1000 nm). Although a wide array of fluorophores are available that are visualized in the red and near‐IR region of the spectrum, with the exception of proteases, there are few long wavelength probes for enzymes. This situation poses a particular challenge for studying the intracellular biochemistry of erythrocytes, the high hemoglobin content of which optically obscures subcellular monitoring at wavelengths less than 600 nm. To address this, tunable fluorescent reporters for protein kinase activity were developed. The probing wavelength is preprogrammed by using readily available fluorophores, thereby enabling detection within the optical window of tissue, specifically in the far‐red and near‐IR region. These agents were used to monitor endogenous cAMP‐dependent protein kinase activity in erythrocyte lysates and in intact erythrocytes when using a light‐activatable reporter.